Selectivley protect some PCs in AD

Is it possible to setup Duo on a few PCs or Windows servers in an AD domain? I want to try out Duo on some critical resources before we commit. Just not sure if mixing is possible in an AD scenario.

Duo for Windows Authentication can be installed on as few or as many domain-joined servers as you wish. Since you install the Duo client application locally on the server, installing it on one has no effect on other servers that don’t have Duo installed.