It is applicable to configure DUO with cisco SSL VPN ( remote access )

it is applicable to configure Two-Factor Authentication with DUO in Cisco SSL VPN ( remote access ), if I used the LOcal database of Cisco FTD as primary authentication, as after I checked the article I found it used LDAP or RADIUS server as a primary authentication

Hi @AAli ,

Perhaps the following KB article will help regarding your inquiry: Can I use Duo to protect Cisco ASA local account logins?

Thanks!

Here are step-by-step instructions to add Duo via RADIUS for only secondary authentication on an ASA. You can keep primary set to local.

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