Can I login into Cisco ISE with DUO Yubikey?

Hello everyone

We are using DUO Cloud Service.
I want to Cisco ISE with DUO Yubikey

Cisco ISE admin login → my id/pw → DUO yubikey - auth ok

How can i using this process?
According to the guide, i need to build a proxy server.
But we are using DUO cloud server.
How can i using this solution?

please help me

If you follow these instructions for RADIUS auth on ISE with the Duo Authentication proxy, at the end you have a configuration where you can use Yubikey OTP as the passcode to log in, appending the passcode to your password like password,vvccccidoutnfedoubhkkcrdounjegecduogndduojh.